Glucovance 500/2.5​mg Tablet

Description

Glucovance 500/2.5mg Tablet: Dual-Action Blood Sugar Control for Type 2 Diabetes

Glucovance 500/2.5mg Tablets combine two well-established antidiabetic medications, Metformin Hydrochloride (500mg) and Glyburide (2.5mg), to provide effective management of blood sugar levels in adults with type 2 diabetes mellitus. This combination therapy offers a convenient treatment option that targets different mechanisms involved in glucose regulation, leading to improved glycemic control.

• Metformin Hydrochloride (500mg): A widely used first-line medication for type 2 diabetes. Metformin primarily reduces glucose production in the liver and improves insulin sensitivity in the body’s tissues, allowing cells to take up glucose more effectively.
• Glyburide (2.5mg): A sulfonylurea that stimulates the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps the body’s cells absorb glucose from the bloodstream, thus lowering blood sugar levels.

What is Glucovance 2.5 500 mg used for?

Glucovance 500/2.5mg is used for the treatment of type 2 diabetes mellitus in adults to improve glycemic control, particularly when:

• Diet and exercise alone are not enough to achieve target blood sugar levels.
• Treatment with either Metformin or Glyburide alone has not provided adequate control.
• A combination of both medications, at these dosages, is deemed appropriate by a doctor.

Glucovance helps to:

• Lower Blood Sugar Levels: Effectively reduces both fasting and postprandial (after-meal) blood glucose levels.
• Improve HbA1c: Lowers HbA1c, a measure of average blood sugar control over the past 2-3 months.
• Address Multiple Aspects of Glucose Regulation: Combines the benefits of increased insulin release (Glyburide) with reduced liver glucose production and improved insulin sensitivity (Metformin).

Is Glucovance and Glucophage the same?

No, Glucovance and Glucophage are not the same, although they are related.

• Glucophage: Contains only Metformin as the active ingredient.
• Glucovance: Contains a combination of Metformin and Glyburide.

Therefore, Glucovance provides a dual mechanism of action, while Glucophage only offers the benefits of Metformin.

Important Considerations:

• Prescription Medication: Glucovance is a prescription medication and should only be taken under the guidance of a healthcare professional.
• Kidney Function: Your doctor will assess your kidney function before starting Glucovance and periodically during treatment. Dose adjustments may be necessary for individuals with kidney problems. Metformin is generally not recommended if kidney function is severely impaired.
• Liver Function: Inform your doctor if you have a history of liver problems.
• Interactions: Inform your doctor about all other medications you are taking, as Glucovance can interact with certain drugs.
• Pregnancy and Breastfeeding: Discuss the risks and benefits with your doctor if you are pregnant or breastfeeding.
• Alcohol: Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and hypoglycemia.

glucovance 500/2.5 side effects:

Common side effects of Glucovance may include:

• Hypoglycemia (Low Blood Sugar): This is more likely due to the Glyburide component. Symptoms include shakiness, sweating, dizziness, confusion, hunger, irritability, and rapid heartbeat.
• Gastrointestinal: Nausea, vomiting, diarrhea, stomach pain, gas, loss of appetite, metallic taste in the mouth. (These are often associated with Metformin and may be reduced by taking the medication with meals).
• Headache
• Weight gain
• Skin rash

Serious side effects are rare but can occur. These may include:

• Lactic Acidosis: A rare but serious buildup of lactic acid in the blood, primarily associated with Metformin. Symptoms include muscle pain, weakness, difficulty breathing, and stomach discomfort. Seek immediate medical attention if you experience these symptoms.
• Severe Hypoglycemia: Can lead to loss of consciousness or seizures.
• Allergic Reactions: Rash, itching, swelling, difficulty breathing.
• Liver problems: Yellowing of the skin or eyes (jaundice), dark urine.

Report any unusual or severe side effects to your doctor immediately.

Dosage and Administration:

• The dosage of Glucovance is individualized and determined by your doctor.
• Glucovance is usually taken once or twice daily with meals.

Price:

• Glucovance 2.5 500 mg price in Pakistan: Rs. 163.00 (Please note that this price might be for a specific pack size. Check with your local pharmacy for accurate pricing.)

Consult with your doctor for proper diagnosis and treatment before using Glucovance 500/2.5mg Tablets.