Description
Treviamet XR 50/1000mg Tablet: Once-Daily Extended-Release for Improved Type 2 Diabetes Control
Treviamet XR 50/1000mg Tablets offer a convenient and effective treatment option for adults with type 2 diabetes mellitus. This medication combines Sitagliptin (50mg), a dipeptidyl peptidase-4 (DPP-4) inhibitor, with Metformin Hydrochloride (1000mg) in an extended-release (XR) formulation. The XR formulation allows for once-daily dosing and provides sustained release of Metformin throughout the day, which can improve tolerability and adherence to the medication regimen.
- Sitagliptin (50mg): Enhances the body’s natural ability to lower blood sugar by increasing the levels of active incretin hormones. These hormones stimulate insulin release after meals and decrease the liver’s production of glucose.
- Metformin Hydrochloride (1000mg) – Extended-Release: A widely used first-line medication for type 2 diabetes. Metformin primarily reduces glucose production in the liver and improves insulin sensitivity in the body’s tissues. The extended-release formulation provides a gradual release of the drug, which can minimize gastrointestinal side effects compared to immediate-release Metformin.
What is Treviamet XR used for?
Treviamet XR is used for the treatment of type 2 diabetes mellitus in adults to improve glycemic control, particularly when:
- Diet and exercise alone do not adequately control blood sugar levels.
- Treatment with either Sitagliptin or Metformin alone has not been sufficient.
- A combination of both medications with the convenience of once-daily dosing is desired.
Treviamet XR helps to:
- Lower Blood Sugar Levels: Effectively reduces both fasting and postprandial (after-meal) blood glucose levels.
- Improve HbA1c: Lowers HbA1c, a measure of average blood sugar control over 2-3 months.
- Provide Convenient Once-Daily Dosing: The extended-release formulation simplifies the medication regimen, potentially improving adherence.
- Potentially Fewer GI Side Effects: The extended-release Metformin may cause fewer gastrointestinal side effects compared to immediate-release Metformin.
Difference between Treviamet and Treviamet XR:
- Treviamet: Contains immediate-release formulations of both Sitagliptin and Metformin. It typically requires twice-daily dosing.
- Treviamet XR: Contains Sitagliptin and an extended-release formulation of Metformin. This allows for once-daily dosing and may reduce gastrointestinal side effects.
treviamet xr 50/1000 side effects:
Common side effects of Treviamet XR may include:
- Gastrointestinal: Diarrhea, nausea, vomiting, stomach pain, gas, indigestion. While the XR formulation may reduce these effects compared to immediate-release Metformin, they can still occur.
- Headache
- Hypoglycemia (Low Blood Sugar): Although less common with this combination than with sulfonylureas, hypoglycemia can occur, particularly if meals are skipped or when combined with other antidiabetic medications.
- Upper respiratory tract infections
- Back pain
Serious side effects are rare but can occur. These may include:
- Lactic Acidosis: A rare but serious buildup of lactic acid in the blood, primarily associated with Metformin. The risk is higher in individuals with kidney problems. Symptoms include muscle pain, weakness, difficulty breathing, and stomach discomfort. Seek immediate medical attention if you experience these symptoms.
- Pancreatitis: Inflammation of the pancreas. Symptoms include severe abdominal pain, nausea, and vomiting.
- Allergic Reactions: Rash, itching, swelling, difficulty breathing.
- Heart Failure
Report any unusual or severe side effects to your doctor immediately.
Important Considerations:
- Prescription Medication: Treviamet XR is a prescription medication and should only be taken under the guidance of a healthcare professional.
- Kidney Function: Your doctor will assess your kidney function before starting Treviamet XR and periodically during treatment. Dose adjustments or discontinuation may be necessary for individuals with kidney problems.
- Interactions: Inform your doctor about all other medications you are taking, as Treviamet XR can interact with certain drugs.
- Pregnancy and Breastfeeding: Discuss the risks and benefits with your doctor if you are pregnant or breastfeeding.
treviamet xr 50/1000 price in Pakistan:
- Treviamet XR 50/1000 price in Pakistan: Rs. 670.00
Consult with your doctor for proper diagnosis and treatment before using Treviamet XR 50/1000mg Tablets.
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