Glucovance 500/5​mg Tablet

Description

Glucovance 500/5mg Tablet: Optimizing Blood Sugar Control in Type 2 Diabetes

Glucovance 500/5mg Tablets combine two widely used antidiabetic medications, Metformin Hydrochloride (500mg) and Glibenclamide (5mg), to provide effective management of blood sugar levels in adults with type 2 diabetes mellitus. This combination therapy offers a comprehensive approach to glycemic control, targeting different mechanisms involved in glucose regulation.

• Metformin Hydrochloride (500mg): A cornerstone medication for type 2 diabetes, Metformin primarily reduces the amount of glucose produced by the liver. It also enhances insulin sensitivity in the body’s tissues, allowing cells to utilize glucose more effectively.
• Glibenclamide (5mg): Also known as Glyburide, this medication belongs to the sulfonylurea class of drugs. Glibenclamide stimulates the beta cells in the pancreas to release more insulin. Insulin is a crucial hormone that helps lower blood sugar levels by enabling glucose uptake into cells.

What is Glucovance 5 500 mg used for? What is glibenclamide 5mg metformin 500mg used for?

Glucovance 500/5mg (Metformin/Glibenclamide) is used for the treatment of type 2 diabetes mellitus in adults to improve glycemic control. It’s typically prescribed when:

• Diet and exercise alone are not sufficient to achieve target blood sugar levels.
• Treatment with either Metformin or Glibenclamide alone has not provided adequate control.
• A physician determines that a combination of these two medications is appropriate for the patient’s needs.

Glucovance 500/5mg helps to:

• Lower Blood Sugar Levels: Effectively reduces both fasting and postprandial (after-meal) blood glucose levels.
• Improve HbA1c: Lowers HbA1c, a key indicator of long-term blood sugar control over the past 2-3 months.
• Address Multiple Aspects of Glucose Regulation: Combines the insulin-stimulating action of Glibenclamide with Metformin’s ability to reduce liver glucose production and improve insulin sensitivity.

Important Considerations:

• Prescription Medication: Glucovance is a prescription medication and should only be taken under the guidance of a healthcare professional.
• Kidney Function: Your doctor will assess your kidney function before starting Glucovance and periodically during treatment. Dose adjustments may be necessary for individuals with kidney problems, and it’s generally not recommended for those with severe kidney impairment.
• Liver Function: Inform your doctor if you have a history of liver problems.
• Interactions: Inform your doctor about all other medications you are taking, as Glucovance can interact with certain drugs.
• Pregnancy and Breastfeeding: Discuss the risks and benefits with your doctor if you are pregnant or breastfeeding.
• Alcohol: Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis (a rare but serious side effect associated with Metformin) and hypoglycemia.

Glucovance 5 500 side effects:

Common side effects of Glucovance may include:

• Hypoglycemia (Low Blood Sugar): This is more likely due to the Glibenclamide component. Symptoms include shakiness, sweating, dizziness, confusion, hunger, irritability, and rapid heartbeat.
• Gastrointestinal: Nausea, vomiting, diarrhea, stomach pain, gas, loss of appetite, a metallic taste in the mouth. (These are often associated with Metformin and may be reduced by taking the medication with meals).
• Headache
• Weight gain
• Skin rash

Serious side effects are rare but can occur. These may include:

• Lactic Acidosis: A rare but serious buildup of lactic acid in the blood, primarily associated with Metformin, especially in individuals with impaired kidney function. Symptoms include muscle pain, weakness, difficulty breathing, and stomach discomfort. Seek immediate medical attention if you experience these symptoms.
• Severe Hypoglycemia: Can lead to loss of consciousness or seizures.
• Allergic Reactions: Rash, itching, swelling, difficulty breathing.
• Liver problems: Although rare, it can occur.

Report any unusual or severe side effects to your doctor immediately.

Glucovance tablet dosage:

The dosage of Glucovance is individualized and determined by your doctor. The usual starting dose is 500mg/2.5mg once or twice daily with meals. The dose may be adjusted by your doctor based on your response to treatment and blood sugar levels.

Always follow your doctor’s instructions carefully regarding dosage and administration.

glucovance 500/5 uses in Urdu:

• گلوکووینس 500/5 کا استعمال:
  • ٹائپ 2 ذیابیطس کے علاج کے لیے
  • خون میں شوگر کی سطح کو کم کرنے کے لیے

Glucovance 500/5 substitute:

There are other brands available in the market that contains Metformin and Glibenclamide in different strengths. Some of them include:

• Gluconil
• Diacon-MF Please consult your doctor before switching the brands.

Price:

• Glucovance 500/5 mg price in Pakistan: Rs. 239.00 (Please note that this price might be for a specific pack size. Check with your local pharmacy for accurate pricing.)

Consult with your doctor for proper diagnosis and treatment before using Glucovance 500/5mg Tablets.