Epival 500mg/5ml Injection

Description

Epival 500mg/5ml Injection (Valproate Sodium): Rapid and Effective Control of Seizures and Status Epilepticus

Epival 500mg/5ml Injection is a sterile, injectable solution containing Valproate Sodium, a form of valproic acid. This medication is a crucial tool in the management of various seizure disorders, particularly in situations where rapid seizure control is necessary or when oral administration is not feasible. It is administered intravenously or intramuscularly by healthcare professionals in a hospital or clinical setting.

What is the use of Epival injection? What is Epival 500mg used for? What is a valproate injection used for?

Epival Injection, including the 500mg/5ml formulation, is primarily used for:

• Status Epilepticus: This is a life-threatening condition characterized by prolonged seizures or a series of seizures without full recovery of consciousness between them. Intravenous valproate is often used as a second-line treatment when other medications are not effective.
• Acute Seizures: When rapid seizure control is needed, such as in a hospital setting during an acute seizure episode.
• Replacement for Oral Therapy: When patients are unable to take oral medications (e.g., due to surgery, gastrointestinal issues, or being unconscious), the injectable form can be used temporarily.
• Bipolar Disorder: In some cases, injectable valproate may be used for the rapid control of severe manic episodes, although this is less common than its use in seizure disorders.

What is the formula for Epival 500mg? Epival injection formula:

The “formula” can be understood in two ways:

• Chemical Formula: Valproate Sodium, the active ingredient, has a chemical formula of C8H15NaO2.
• Formulation: Epival 500mg/5ml Injection contains 500mg of Valproate Sodium in each 5ml of solution. It will also contain inactive ingredients, which are pharmacologically inert substances used for purposes like sterilization and stabilization. These may include water for injection and potentially other agents to adjust pH or tonicity. The exact inactive ingredients can be found in the product’s packaging insert.

Epival injection dose:

The dosage of Epival Injection is highly individualized and must be determined by a qualified healthcare professional. The appropriate dose depends on:

• The condition being treated: Status epilepticus will require a different dose than a single seizure episode.
• The patient’s weight: Dosage is often calculated based on body weight (mg/kg).
• The patient’s age and overall health: Renal and liver function can affect drug metabolism.
• Response to treatment: The doctor will monitor the patient’s response and may adjust the dosage.
• Other medications: Epival can interact with other drugs.

A typical loading dose for status epilepticus might be 20-40 mg/kg given intravenously, followed by a maintenance dose. However, this is just an example, and the actual dose will be determined by the treating physician.

Epival injection alternative:

Several alternative medications can be used to treat seizures and status epilepticus, depending on the specific situation. These may include:

• Other Anticonvulsants: Phenytoin, Levetiracetam, Lorazepam, Diazepam, Midazolam, Phenobarbital, and others.
• Mood Stabilizers (for Bipolar): Lithium, Lamotrigine, and others.

The best alternative will be determined by a doctor based on the patient’s needs.

Epival injection side effects:

Common side effects of Epival Injection may include:

• Injection site reactions: Pain, redness, or swelling at the injection site.
• Gastrointestinal: Nausea, vomiting, stomach pain.
• Neurological: Drowsiness, dizziness, tremor, headache.
• Other: Hair loss (usually temporary), changes in liver function tests.

Serious side effects are less common but can occur. These may include:

• Liver problems: Yellowing of the skin or eyes (jaundice), dark urine.
• Pancreatitis: Severe abdominal pain, nausea, vomiting.
• Low platelet count: Easy bruising or bleeding.
• Allergic reactions: Rash, itching, swelling, difficulty breathing.
• Suicidal thoughts: A rare but serious side effect.

Report any unusual or severe side effects to your doctor immediately.

Important Considerations:

• Prescription Only: Epival Injection is a prescription medication and should only be administered under the direct supervision of a healthcare professional in a hospital or clinical setting.
• Allergies: Inform your doctor about any known allergies, especially to valproic acid or related compounds.
• Medical History: Disclose your full medical history and any other medications you are taking to your doctor.
• Pregnancy: Valproate can cause serious birth defects. Pregnant women or those planning pregnancy should avoid this medication unless absolutely necessary and under strict medical supervision.

Inj Epival 500mg price in Pakistan & Epival Injection price:

• Epival Injection price: Rs. 240.00 (This likely refers to the 500mg/5ml formulation)

Consult with a healthcare professional for proper diagnosis and treatment before using Epival 500mg/5ml Injection.